Despite a general downward movement in U.S. equity markets on Monday, with the Dow Jones Industrial Average slipping by approximately 200 points, select large-cap stocks advanced sharply during the trading session. Noteworthy among these was Planet Labs PBC (NYSE:PL), which saw its shares climb 7% to $24.29. This uptick came on the heels of the company's announcement of a substantial multi-year agreement valued in the nine figures with the Swedish Armed Forces, signaling a significant expansion in its satellite imaging and data services business.
Beyond Planet Labs, multiple other stocks demonstrated robust gains across various sectors. Wheels Up Experience Inc (NYSE:UP), specializing in private aviation services, soared by over 30%, closing at $0.89, reflecting heightened investor optimism about the company’s growth prospects.
The biopharmaceutical sector exhibited particularly strong momentum. Day One Biopharmaceuticals Inc (NASDAQ:DAWN) surged 24.7%, reaching a price of $11.15. This appreciable rise coincided with the company reporting preliminary net product revenue for 2025 from its OJEMDA therapy of $155.4 million, representing a 172% increase compared to the prior year. This substantial growth highlights increasing market adoption and sales expansion for the treatment.
Similarly, Rxsight Inc (NASDAQ:RXST) shares appreciated by 22.7% to $10.85 following the disclosure of preliminary fourth-quarter revenue amounting to $32.6 million, underscoring strong commercial performance momentum. Beam Therapeutics Inc (NASDAQ:BEAM) also reported forward-looking business initiatives, announcing its 2026 strategic priorities aligned with the U.S. Food and Drug Administration regarding a potential accelerated approval path for its BEAM-302 therapy. The company closed the year 2025 with a robust preliminary estimated cash balance of $1.25 billion, supporting its advancement plans. This news stimulated a 22% rise in Beam’s share price to $33.60.
Other considerable gains in the biopharma and adjacent sectors included Zenas Biopharma Inc (NASDAQ:ZBIO), which increased by 23.2% to $19.81, and Adaptive Biotechnologies Corp (NASDAQ:ADPT), which rose 13.4% to $17.86 after reporting preliminary fourth-quarter revenue of $72 million and projecting 2025 revenue of $277 million. Twist Bioscience Corp (NASDAQ:TWST) also benefited from robust fiscal first-quarter 2026 preliminary revenue figures of $103.7 million, marking a 17% year-over-year increase, which propelled its shares up 11.7% to $39.48.
Expanding beyond biopharma, Starfighters Space Inc (NYSE:FJET) shares climbed 17.7% to $13.95, demonstrating investor interest in space-related ventures.
SunOpta Inc (NASDAQ:STKL), a company specializing in organic and plant-based foods, advanced 17.5% to $4.37 subsequent to raising its fiscal year 2025 sales guidance, signaling confidence in future revenue growth.
Precious metals mining stocks also posted gains amid commodity price movements. Hycroft Mining Holding Corporation (NASDAQ:HYMC) increased by 16.7%, ending the session at $31.67, while Coeur Mining Inc (NYSE:CDE) advanced 6.5% to $21.73. The rise in precious metals prices occurred alongside a Department of Justice criminal investigation into Federal Reserve Chair Jerome Powell. This development has heightened investor concern over the Federal Reserve's independence, leading market participants to seek safe-haven assets amid weakening U.S. dollar conditions.
Technology and storage sectors reflected positive momentum as well, with Pure Storage Inc (NYSE:PSTG) gaining 9.4% to $73.30 and Tempus AI Inc (NASDAQ:TEM) rising 9.2% to $72.40. Tempus reported preliminary revenue estimates of approximately $1.27 billion for 2025, representing an 83% year-over-year increase, further boosting investor sentiment.
Lastly, Abivax SA (NASDAQ:ABVX) recorded an 8.3% gain, concluding Monday’s session at $123.88, while Alibaba Group Holding Ltd – ADR (NYSE:BABA) increased 8.1% to $163.11 amidst broader market dynamics.
This diverse array of stock market surges came as broader indices softened, illustrating a market environment marked by sector- and company-specific developments driving selective investor enthusiasm.